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DEPARTMENT OF CHEMISTRY
Robert F. Volp
B.S.-University of Wisconsin-Stevens Point
Ph.D.-University of Wisconsin-Madison
Associate Professor
Biochemical Toxicology
Office: 309 Blackburn
Phone: 270-809-6598
E-mail: robert.volp@murraystate.edu
Dr. Volp's interests
include biotransformation and biochemical toxicity of halogenated
aliphatic hydrocarbons, especially halopropanes. He is also active
in enzymology of glucuronate conjugation, as well as use of high
performance liquid chromatography in studying biochemical reactions.
Selected Publications
Volp, R. F. "Glucuronidation in 4-Chlorobiphenyl Metabolism by Rat and Human Liver Microsomes,"
Drug Metab. Dispos. 1988, 16, 650-652.
Schnellmann, R. G. ; Volp, R. F.; Putnam, C. W.; Sipes, I. G. "The Hydroxylation, Dechlorination, and Glucuronidation of
4,4'-Dichlorobiphenyl (4-DCB) by Human Hepatic Microsomes," Biochem. Pharmacol.
1984, 33, 3503-3509.
Volp, R. F.; Sipes, I. G.; Falcoz; C.; Carter, D. E.; Gross, J. F. "Disposition of 1,2,3-Trichloropropane in the Fischer 344
Rat: Conventional and Physiological Pharmacokinetics," Toxicol. Appl. Pharmacol.
1984, 75, 8-17.
Bock, K. W.; Bock-Hennig, B. S.; Lilienblum, W.; Pfeil, H.; Volp, R. F. "Roles of
UDP-Glucuronosyltransferase in the Inactivation of Benzo(a)pyrene," in "Biological Reactive Intermediates-II," (Snyder, R.; Parke, D. V.; Kocsis, J. J.;
Jollow, D. J.; Gibson, C. G.; Witmer, C. M., eds.) Plenum Press, New York, pp. 53-73.
Volp, R. F.; Lage, G. L. "Digitoxin Metabolism by Rat, Mouse, and Rabbit: NADPH Requirement and Spironolactone
Effect," Res. Commun. Chem. Pathol. Pharmacol. 1982, 38, 501-504.
Bock, K. W.; Bock-Hennig, B. S.; Lilienblum, W.; Volp, R. F. "Release of Mutagenic Metabolites of Benzo(a)pyrene from
the Perfused Rat Liver after Inhibition of Glucuronidation by Salicylamide",
Chem. Biol. Interactions. 1981, 36, 167-177.
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