BA, MS, University of Montana; PhD, University of Wisconsin-Madison. My lab is broadly
interested in the biological importance and biotechnological application of inteins.
Inteins, or internal proteins, are self-catalytic, mobile genetic elements removed
from host genes through protein splicing. Abundant in the microbial world, inteins
have recently emerged as adaptive regulatory elements, representing a novel and potentially
widespread form of posttranslational regulation. Further, the power of inteins to
make and break peptide bonds has been utilized extensively in biotechnology, and my
lab seeks to develop new applications of this chemistry.